Rational optimization of drug-target residence time: insights from inhibitor binding to the Staphylococcus aureus FabI enzyme-product complex.

Andrew Chang; Johannes Schiebel; Weixuan Yu; Gopal R Bommineni; Pan Pan; Michael V Baxter; Avinash Khanna; Christoph A Sotriffer; Caroline Kisker; Peter J Tonge

doi:10.1021/bi400413c

Rational optimization of drug-target residence time: insights from inhibitor binding to the Staphylococcus aureus FabI enzyme-product complex.

Identifier:nobleid.org/w1/20260515/34C01BEE

Type:Journal Article

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Christoph A Sotriffer

Caroline Kisker

Peter J Tonge

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Rational optimization of drug-target residence time: insights from inhibitor binding to the Staphylococcus aureus FabI enzyme-product complex.

Identifier:nobleid.org/w1/20260515/34C01BEE

Type:Journal Article

0 views

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Christoph A Sotriffer

Caroline Kisker

Peter J Tonge

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