Naphthyl and coumarinyl biarylpiperazine derivatives as highly potent human beta-secretase inhibitors. Design, synthesis, and enzymatic BACE-1 and cell assays.

Cédrik Garino; Taisuke Tomita; Nicolas Pietrancosta; Younes Laras; Roselyne Rosas; Gaëtan Herbette; Bernard Maigret; Gilles Quéléver; Takeshi Iwatsubo; Jean-Louis Kraus

doi:10.1021/jm0602864

Naphthyl and coumarinyl biarylpiperazine derivatives as highly potent human beta-secretase inhibitors. Design, synthesis, and enzymatic BACE-1 and cell assays.

Identifier:nobleid.org/w1/20260515/AF155EBF

Type:Journal Article

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Naphthyl and coumarinyl biarylpiperazine derivatives as highly potent human beta-secretase inhibitors. Design, synthesis, and enzymatic BACE-1 and cell assays.

Identifier:nobleid.org/w1/20260515/AF155EBF

Type:Journal Article

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