Lysosomotropism of basic cathepsin K inhibitors contributes to increased cellular potencies against off-target cathepsins and reduced functional selectivity.

Jean-Pierre Falgueyret; Sylvie Desmarais; Renata Oballa; W Cameron Black; Wanda Cromlish; Karine Khougaz; Sonia Lamontagne; Frederic Massé; Denis Riendeau; Sylvie Toulmond

doi:10.1021/jm0504961

Lysosomotropism of basic cathepsin K inhibitors contributes to increased cellular potencies against off-target cathepsins and reduced functional selectivity.

Identifier:nobleid.org/w1/20260515/CD7ACE3C

Type:Journal Article

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Lysosomotropism of basic cathepsin K inhibitors contributes to increased cellular potencies against off-target cathepsins and reduced functional selectivity.

Identifier:nobleid.org/w1/20260515/CD7ACE3C

Type:Journal Article

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