Multiomic evaluation of TEV-56278, a PD-1-targeted attenuated IL-2 molecule, in a human ex vivo tumor model and association with immune activation with enhanced effector CD8 T cell selectivity.

Tamir, Ayala; Eraslan, Rukiye-Nazan; O’Mara, Edward; Kumar, Gaurav; Shuparski, Andrew; Ruppova, Klara; Honsa, Pavel; Andreoli, Mirko; Mediratta, Devin; Nayar, Shikha

doi:10.1200/jco.2025.43.16_suppl.e14506

Multiomic evaluation of TEV-56278, a PD-1-targeted attenuated IL-2 molecule, in a human ex vivo tumor model and association with immune activation with enhanced effector CD8 T cell selectivity.

Ayala Tamir, Rukiye-Nazan Eraslan, Edward O’Mara, Gaurav Kumar and 6 more

Eleni P Mimitou

NobleIDNI9P23W77R42S92

Type:Journal Article

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Multiomic evaluation of TEV-56278, a PD-1-targeted attenuated IL-2 molecule, in a human ex vivo tumor model and association with immune activation with enhanced effector CD8 T cell selectivity | NobleID